INTRATHECAL INJECTION OF THE SECRETOME FROM ALS MOTOR NEURONS REGULATED FOR MIR-124 EXPRESSION PREVENTS DISEASE OUTCOMES IN SOD1-G93A MICE

Intrathecal Injection of the Secretome from ALS Motor Neurons Regulated for miR-124 Expression Prevents Disease Outcomes in SOD1-G93A Mice

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with short life expectancy and no effective therapy.We previously identified upregulated miR-124 in NSC-34-motor neurons (MNs) Beef expressing human SOD1-G93A (mSOD1) and established its implication in mSOD1 MN degeneration and glial cell activation.When anti-miR-124-treated mSOD1 M

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Patterns of Roughness in Global Literacy Rates

This study examines the literacy rate of 204 countries all over the world focusing on both male and female population with ages 15 years old and above.The source indicates that of all the illiterate adults in the world, two-thirds are women.Data Eyebrow Enhancers also reveal that extremely low literacy rates are concentrated in three regions: Afgha

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Multimodality imaging of paragangliomas of the head and neck

Abstract Paragangliomas arise from paraganglion cells which serve varied regulatory tasks in the body.When these cells demonstrate neoplasia within the head and neck, they typically present in characteristic locations including the carotid space, the jugular foramen, the middle ear, Dab Pads and along the course of the vagus nerve.The goal of this

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